Bramble provides extensive good qualities, however, it will be on most use the classes that use Poison as a main attack. It can roll with 25-50% extra Poison Skill damage, which any poison-flinger will like, especially when combined with Trang'Oul's Claws gloves, which give one more 25% Poison damage. The Thorns damage is interesting because it will extend to Mercenaries, Necro or Druid summons, and Valkyrie.
Bramble Strengths and Weaknesses
Strengths of the Bramble Runeword:
Excellent poison bonuses for Poison-wielding classes
100% Poison Resist
Interesting mana restoration/improvement stats
Emanating Thorns aura particularly helpful to classes with many different summoned minions
Weaknesses of the Bramble Runeword:
Large swings in how this armor will roll
Thorns aura is primarily helpful to summoned minions because most classes using this won't like to get hit (even though Faster Hit Recovery incorporated with this armor is a nice touch)
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Bramble's main problem is incorporated in the wide range of rolls you will get, which will greatly alter this armor's effectiveness within its best features. Bramble also rolls between 25% and 50% Poison Skill damage, which is a significant difference. An Amazon's Level 20 Plague Javelin can deliver 1888-1937 damage, which could range from 2360-2421 at 25% to 2832-2905 at 50%. The damage returned percentage from a level 15 Thorns aura along with a level 21 Thorns aura is 810% to 1210%, a positive change of 400%. The more minions you routinely have, the greater important a higher roll around the Thorns aura becomes.
Bramble Recommendations
Runewords vary on the suitability for various classes and specs, in addition to the utility for that various Mercenaries. This next section will discuss what classes and specs could make the most out of Bramble, whether you should look at using Bramble together with your Mercenary follower, what base to consider, and where you can acquire Runes.
Best Classes and Specs for that Bramble Runeword
This is a Runeword that has "poison spec" written throughout it. It is going to be of most interest to Poison-focused Necromancer builds, which routinely have a lot of summoned minions together, in addition to Plague Javazons, who will like the extra Poison Skill damage. It raises some intriguing possibilities with Werewolf druids who spec into Rabies, even though this hasn't typically been a well-known build. Still, using the 2.4 changes towards the Druid, where they can call up almost all their wolves and bears simultaneously, will bear some consideration.